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为确定喉癌手术安全切线距离，以组织病理学方法对64例喉癌标本进行观察；并结合临床及随访，对癌周病灶扩散情况、不同切缘距离患者的肿瘤复发率及病人的短期生存车进行研究。发现癌周粘膜中、重度非典型增生及粘膜下浸润亚临床癌灶多在肉眼边界外5mm以内（76．6％），建议以5mm作为切缘的安全标准。同时认为，术中肉眼对肿瘤边界的判断较可靠。阳性切缘患者较阴性者术后复发率高、生存率低，阳性切缘的好发部位依次为：前位、侧后位、前上位及环后位。与阳性切缘显著相关的因素是肿瘤发生部位、T分级及N分级。
In order to determine the safe tangential distance of laryngeal carcinoma, 64 cases of laryngeal carcinoma specimens were observed by histopathology. Combined with clinical and follow-up, the tumor recurrence rate and short-term survival of patients with peritumoral lesions were analyzed. Car for research. Found in the cancer week mucosa, severe atypical hyperplasia and submucosal subclinical subclinical foci more than 5 mm outside the eye border (76.6%), 5 mm recommended as a margin of safety standards. At the same time, intraoperative intraocular assessment of the tumor boundary more reliable. Patients with positive margin had a higher incidence of postoperative recurrence and a lower survival rate. The positive location of the positive margin was anterior, posterior, anterior and posterior. Significantly correlated with the positive margin of the tumor site, T grade and N grade.