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目的:探讨双水平正压呼吸支持(bilevelpositiveairwaypressure,BiPAP)治疗支气管哮喘(支哮)合并阻塞性睡眠呼吸暂停综合征(obstructivesleepapneasyndromes,OSA)患者的疗效。方法:51例支哮合并OSA患者,随机分为治疗组(30例,在常规治疗的基础上予BiPAP治疗)与对照组(21例,单纯药物常规治疗),进行疗效比较。结果:治疗组临床显效率达100%,30例病人自主症状明显改善,治疗前后的肺功能、血压、低血氧等指标有明显的提高,对照组病人缺氧、呼吸暂停持续存在。结论:支哮合并OSA病人在药物治疗的基础上,给予BiPAP治疗比单用药物疗效显著。
Objective: To investigate the efficacy of bilevel positive airway pressure (BiPAP) in the treatment of patients with bronchial asthma (asthma) and obstructive sleep apnea syndrome (OSA). Methods: Totally 51 patients with OSA complicated with OSA were randomly divided into treatment group (30 cases treated with BiPAP on the basis of routine treatment) and control group (21 cases treated with conventional drug only). Results: The clinical effective rate of the treatment group was 100%. The symptoms of 30 patients were significantly improved. The indexes of pulmonary function, blood pressure and hypoxemia were significantly improved before and after treatment. The hypoxia and apnea persisted in the control group. Conclusion: The treatment of bronchial asthma combined with OSA is more effective than single-drug treatment on the basis of drug treatment.