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目的:探讨自拟宣肺平喘汤对慢性阻塞性肺病(COPD)急性发作患者临床疗效。方法:选取医院自2009—2012年期间收治的COPD患者60例作为研究对象,依据治疗方法不同分为治疗组和对照组;对照组给予抗生素治疗,治疗组在对照组基础上给予自拟宣肺平喘汤治疗。结果:治疗后,治疗组症状积分降到(2.56±1.12)分,总有效率为96.67%;对照组症状积分降到(4.18±2.96)分,总有效率为86.67%;治疗组优于对照组(P<0.05)。两组血常规、肺功能、血气分析检查结果均较治疗前明显改善,且治疗组优于对照组(P<0.05)。两组患者的血清CRP水平均较治疗前明显降低(P<0.05),其中治疗组低于对照组(P<0.05)。结论:自拟宣肺平喘汤能有效缓解COPD患者的临床症状,降低血清炎症水平。
Objective: To investigate the clinical efficacy of xuanfei pingchuan decoction in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: Sixty patients with COPD admitted to the hospital from 2009 to 2012 were selected as study subjects and divided into treatment group and control group according to different treatment methods. The control group was treated with antibiotics. The treatment group was given self-declared Xuanfei Pingchuan soup treatment. Results: After treatment, symptom score of the treatment group dropped to (2.56 ± 1.12) points, the total effective rate was 96.67%; symptom score of the control group dropped to (4.18 ± 2.96) points, the total effective rate was 86.67%; treatment group was superior to the control Group (P <0.05). Blood test, pulmonary function test and blood gas test results of both groups were significantly improved compared with that before treatment, and the treatment group was better than the control group (P <0.05). Serum CRP levels in both groups were significantly lower than before treatment (P <0.05), and the treatment group was lower than the control group (P <0.05). Conclusion: Xuanfei Pingchuan Decoction can effectively relieve the clinical symptoms of COPD patients and reduce the level of serum inflammation.