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作者认为治疗慢性重型心力衰竭首选的一线药物应满足以下标准:①能快速缓解症状;②能降低死亡率;③能改变其自然病程;④较安全且能被患者所耐受。据此,经大量随机、双盲、安慰剂对照的临床研究证实: 利尿剂是一种缓解症状较快,比较安全地控制心衰的口服药物,但单独使用时尚不能达到长期满意、稳定的治疗目的。洋地黄类强心药物可增加心肌收缩力,减少心衰反复发作的频度,减少利尿剂的用量,增加运动耐受性,且大部份心衰病人能长期耐受此药的治疗,具有其他药物不能取代的效用,是治疗慢性心衰的重要药物之一,但对长期成活率的影响尚不清
The authors believe first-line drugs for the treatment of chronic severe heart failure should meet the following criteria: ① can quickly relieve symptoms; ② reduce mortality; ③ can change its natural history; ④ safer and patient tolerance. Accordingly, a large number of randomized, double-blind, placebo-controlled clinical studies have shown that: diuretics is an oral medication to relieve symptoms faster and safer to control heart failure, but can not achieve long-term satisfaction and stable treatment alone purpose. Digitalis concentric drugs can increase myocardial contractility, reduce the frequency of recurrent heart failure, reduce the amount of diuretics, increased exercise tolerance, and most patients with heart failure can long-term treatment of this drug, with Other drugs can not replace the effectiveness of the treatment of chronic heart failure is one of the important drugs, but the impact on long-term survival is not clear