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目的：观察正常妊娠中、晚期孕妇血液流变学参数的变化。方法：运用ＣＦ型围产监测仪检测左室射血阻抗、动脉特性阻抗、动脉终端阻抗及总外周阻抗，以研究外周阻力变化；检测毛细血管血流速度及微循环灌注连续性比率，探讨微循环改变；同时探讨血容量与血粘度变化。结果：妊娠后５～１０个月左室射血阻抗、动脉特性阻抗、动脉终端阻抗及总外周阻抗较对照组明显减少（Ｐ＜０．０１），各月间上述指标无明显差异（Ｐ＞０．０５）；孕妇毛细血管血流速度明显加快（Ｐ＜０．０１），至妊娠１０月达高峰；毛细血管灌注连续性比率则明显下降（Ｐ＜０．０１），以妊娠１０个月最低。该期间内，孕妇血容量明显增加（Ｐ＜０．０１），血粘度在孕５个月时最低，以后渐回升，至孕１０个月时已恢复正常水平。结论：正常妊娠中、晚期孕妇血管外周阻力降低，微循环功能增强，血容量增加，血粘度以妊娠中期最低，以后渐增加，至足月时恢复妊娠前水平。
Objective: To observe the changes of hemorrheological parameters in the middle and late pregnant women. Methods: Left ventricular ejection resistance, arterial characteristic impedance, arterial terminal impedance and total peripheral impedance were measured by CF type of perinatal monitor to study the change of peripheral resistance; the capillary blood flow velocity and microcirculation perfusion continuity ratio Cycle changes; at the same time to explore changes in blood volume and blood viscosity. Results: Left ventricular ejection resistance, arterial characteristic impedance, arterial terminal impedance and total peripheral impedance decreased significantly (P <0.01) 5 to 10 months after pregnancy, there was no significant difference between the above indexes in each month (P> 0.05). The capillary blood flow velocity of pregnant women accelerated significantly (P <0.01), and reached the peak in the third trimester of pregnancy. The capillary perfusion continuity rate decreased significantly (P <0.01) lowest. During this period, the blood volume of pregnant women increased significantly (P <0.01). The blood viscosity was the lowest at 5 months of pregnancy and gradually rose back to the normal level after 10 months of pregnancy. Conclusion: The normal peripheral blood of pregnant women and late pregnant women have lower peripheral resistance, microcirculation function, blood volume increase, blood viscosity is the lowest in the second trimester of pregnancy, and then increase gradually, to full-term recovery of pre-pregnancy levels.