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目的:分析飞秒激光小切口角膜基质透镜取出术(SMILE)术中并发症及其处理。方法:回顾性病例研究。郑州大学第一附属医院2018年7月1日至2019年6月28日进行的SMILE手术者700例(1 390眼),分析术中的并发症及处理。结果:其中,1 387眼顺利完成手术,仅3眼改行飞秒激光LASIK手术。术中有57眼发生并发症,包括负压脱失4眼,不透明气泡层13眼,黑斑9眼,边缘切口撕裂6眼,角膜基质透镜撕裂或组织残留4眼,角膜基质透镜分离取出困难6眼以及其他并发症15眼。这些术中并发症均得到适当的处理,术后3个月的裸眼视力均达到术前最佳矫正视力水平。结论:SMILE手术存在一定比例的术中并发症,可能影响视力的恢复,但术中及时正确的处理可使最终视力不受影响。“,”Objective:To analyze the intraoperative complications and their management of small incision lenticule extraction (SMILE).Methods:A retrospective case study.A total of 1 390 eyes of 700 patients underwent SMILE from Jul.1st 2018 to Jun.28th 2019 in First Affiliated Hospital of Zhengzhou University.The complications and treatment during the operation were analyzed.Results:Among 1 390 eyes of 700 cases, the operations successfully completed in 1 387 eyes and only 3 eyes were converted to femtosecond laser LASIK.Complications occurred in 57 eyes during the operation, included 4 eyes with suction loss, 13 eyes with opaque bubble layer, 9 eyes with dark spots, 6 eyes with laceration of side incisions, 4 eyes with corneal stroma lens tear or tissue residue, 6 eyes with difficulty in separating and removing the corneal stroma lens and other complications in 15 eyes.These intraoperative complications were properly managed, and the uncorrected visual acuity at 3 months after surgery reached the level of the best corrected visual acuity before surgery.Conclusion:There is a certain proportion of intraoperative complications in SMILE surgery, which can affect the recovery of visual acuity, but timely and proper treatment during surgery can keep the final vision unaffected.