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目的探讨复发性大肠癌的病因及其防治措施、再手术方法。方法对1997～2009年我院36例大肠癌术后复发患者的临床资料进行回顾分析,有6例患者行放化疗治疗,30例进行了再次手术治疗,其中23例根治性切除,7例姑息性切除。结果复发病例经过放化疗及手术治疗后,效果满意,无围手术期死亡病例,30例再次行根治术的病例术后生存时间为9～48个月,中位生存时间为28个月,其中行大肠根治术者生存时间为12～48个月,行姑息切除者生存时间为8～27个月。仅行保守放化疗的6例患者,中位生存期为15个月。结论预防术后大肠癌复发的重点在于手术的彻底性和术中无瘤操作,外科手术联合放化疗在内的综合治疗,可改善预后,延长复发者的存活时间。
Objective To investigate the etiology and prevention and treatment of recurrent colorectal cancer and its reoperation. Methods The clinical data of 36 patients with postoperative recurrence of colorectal cancer in our hospital from 1997 to 2009 were retrospectively analyzed. Six patients underwent radiotherapy and chemotherapy and another 30 underwent reoperation. Among them, 23 patients underwent radical resection and 7 patients underwent palliative treatment Sexual removal. Results The recurrence cases were treated with radiotherapy and chemotherapy and surgery, the results were satisfactory, no perioperative deaths, 30 cases of radical surgery again survival time was 9 to 48 months, the median survival time was 28 months, of which Colorectal cancer radical surgery survival time of 12 to 48 months, palliative resection of the survival time of 8 to 27 months. Six patients with conservative chemoradiation received a median survival of 15 months. Conclusion The prevention of postoperative recurrence of colorectal cancer focuses on the thoroughness of the surgery and the operation of tumor-free operation and surgery combined with chemoradiotherapy to improve the prognosis and prolong the survival time of recurrence patients.