妊娠期急性脂肪肝(AFLP)是产科的危急重症,起病急、进展快、病情凶险,一直以来都是产科非常棘手的一个疾病。因此,早期的识别尤为重要,主要以烦渴、恶心等上消化道症状为主,结合血清学指标共同完成诊断。AFLP的既往死亡率较高,一旦诊断立即终止妊娠,随后行人工肝支持治疗,通常可获得良好的母婴结局。 Acute fatty liver during pregnancy (AFLP) is an obstetric critical illness, acute onset, rapid progress, dangerous condition, has always been a very obstetric maternity disease. Therefore, the early identification is particularly important, mainly polydipsia, nausea and other upper gastrointestinal symptoms, combined with serological indicators to complete the diagnosis. Previous AFLP mortality rates are high, and once diagnosed immediately after termination of pregnancy, followed by artificial liver support therapies usually yield good maternal-infant outcomes.