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目的:比较青春期和成年多囊卵巢综合征患者(polycysticovarysyndrome,PCOS)在临床表现、血激素水平、卵巢形态等方面的异同。方法:对31例青春期和141例成年PCOS患者进行血激素放免测定和卵巢B超检查。结果:月经稀发、闭经、多毛和肥胖在青春期组发生的百分比与成年组间差异无统计学意义。月经不规则在青春期组发生的百分比为29.04%,显著高于成年组的7.10%。成年组的卵巢体积和体重指数(BMI)显著高于青春期组,BMI与年龄弱相关(r=0.26,P<0.05)。两组PCOS患者间血激素水平差异无统计学意义。结论:PCOS可能始发于青春期,其临床表现和内分泌特征并不随年龄变化而改变
Objective: To compare the similarities and differences of clinical manifestations, blood hormone levels and ovarian morphology between adolescent and adult patients with polycystic ovarysyndrome (PCOS). Methods: Thirty-one adolescent and 141 adult PCOS patients underwent radioimmunoassay and ovarian ultrasonography. Results: There was no significant difference in the percentage of menstrual hair loss, amenorrhea, hirsutism and obesity in adolescent group compared with that in adult group. The incidence of menstrual irregularities in the adolescent group was 29.04%, significantly higher than that in the adult group (7.10%). The ovarian volume and body mass index (BMI) of adult group were significantly higher than that of adolescent group, and BMI was weakly correlated with age (r = 0.26, P <0.05). There was no significant difference in serum hormone levels between the two groups of PCOS patients. Conclusions: PCOS may originate in adolescence, its clinical manifestations and endocrine characteristics do not change with age