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目的探讨膀胱嗜铬细胞瘤的诊断及手术治疗方法。方法回顾性分析2003年5月—2010年10月5例膀胱嗜铬细胞瘤的诊治过程。术前均行超声、CT、膀胱镜及儿茶酚胺和香草基扁桃酸检查,5例术前均获得定位及定性诊断。所有病例术前准备10～14 d后行开放膀胱部分切除术,其中1例行输尿管膀胱再植术。结果 5例术后均恢复良好,术后病理均明确诊断,无恶变;术后随访1～7年,血压正常,无肿瘤复发。结论超声、CT、膀胱镜是膀胱嗜铬细胞瘤最主要的定位诊断,儿茶酚胺和香草基扁桃酸是最主要的定性诊断;手术是治疗膀胱嗜铬细胞瘤的最有效方法,围术期处理是手术成功的基础,开放膀胱部分切除术仍是嗜铬细胞瘤治疗的首选术式。
Objective To investigate the diagnosis and surgical treatment of bladder pheochromocytoma. Methods The diagnosis and treatment of bladder pheochromocytoma from May 2003 to October 2010 were retrospectively analyzed. Preoperative ultrasound, CT, cystoscopy and catecholamines and vanillyl mandelic acid examination, 5 cases were preoperative localization and qualitative diagnosis. All cases were preoperatively scheduled for 10 ~ 14 days after partial open partial cystectomy, of which 1 case of ureteral bladder replantation. Results All the 5 cases recovered well after operation. The postoperative pathology was well diagnosed with no malignant transformation. The patients were followed up for 1 to 7 years and had normal blood pressure and no tumor recurrence. Conclusion Ultrasound, CT and cystoscopy are the most important diagnostic methods for diagnosis of bladder pheochromocytoma. Catecholamine and vanillyl mandelate are the most important diagnostic methods. Surgery is the most effective method for the treatment of pheochromocytoma of the bladder. Perioperative management is The basis of successful operation, partial open partial excision of the bladder is still the preferred surgical treatment of pheochromocytoma.