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目的探讨酒精性肝硬化的临床特点及诊治方法。方法对106例酒精性肝硬化患者临床资料进行回顾性分析。结果酒精性肝硬化占同期住院肝硬化总数的8.1%;其血清谷氨酰基转移酶(GGT)、天冬氨酸氨基转移酶(AST)/血清丙氨酸基转移酶(ALT)、血尿酸(UA)等升高较明显,易出现胆囊炎、胆石症和胰腺炎。结论酒精性肝硬化的治疗以戒酒和支持治疗为主。总体上酒精性肝硬化组的预后比肝炎后肝硬化组稍好,但晚期预后二者差别不大。
Objective To investigate the clinical features and diagnosis and treatment of alcoholic cirrhosis. Methods The clinical data of 106 patients with alcoholic cirrhosis were analyzed retrospectively. Results Alcoholic cirrhosis accounted for 8.1% of the total hospitalized cirrhosis in the same period. Serum glutamyl transferase (GGT), aspartate aminotransferase (AST), serum alanyltransferase (ALT), serum uric acid (UA) increased more obvious, prone to cholecystitis, cholelithiasis and pancreatitis. Conclusion The treatment of alcoholic cirrhosis is based on abstinence and supportive care. In general, the prognosis of alcoholic cirrhosis group slightly better than the post-hepatitis cirrhosis group, but the late prognosis is not very different between the two.