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目的对比达英-35和雌孕激素治疗青春期功血疗效,为青春期功血临床治疗提供参考。方法选取2012年9月~2013年9月本院收治的60例青春期功血患者,随机分成治疗组和对照组每组30例,其中治疗组采用达英-35进行治疗,对照组使用雌孕激素进行治疗,治疗后分别观察两组患者止血时间、副反应、突破性出血等情况。结果治疗组止血时间、控制出血时间短于对照组,两组相比P<0.05表示差异有统计学意义。治疗组中3例患者出现轻微的乳房胀痛、恶心症状,不过患者能够忍受,未出现其他副反应。对照组中8例患者出现呕吐、恶心症状,服用维生素B6后症状有所缓解,4例患者出现了突破性出血。两组患者对比P<0.05,表示差异有统计学意义。结论使用达英-35治疗青春期功血疗效显著,副作用小,应在临床实践中推广应用。
Objective To compare the efficacy of Da-Ying-35 and estrogen and progesterone in the treatment of adolescent dysfunctional uterine bleeding, and provide reference for the clinical treatment of adolescent dysfunctional uterine bleeding. Methods Sixty patients with adolescent dysfunctional uterine bleeding treated in our hospital from September 2012 to September 2013 were randomly divided into treatment group (30 cases) and control group (30 cases), in which the treatment group was treated with Ying Ying-35 and the control group Hormones were treated, after treatment were observed in two groups of patients bleeding time, side effects, breakthrough bleeding and so on. Results The treatment group bleeding time, bleeding time control shorter than the control group, P <0.05 compared with the two groups showed statistically significant differences. Three patients in the treatment group had mild breast tenderness and nausea, but patients were able to tolerate no other side effects. Eight patients in the control group developed symptoms of vomiting and nausea. After taking vitamin B6, their symptoms were relieved, and breakthrough bleeding occurred in 4 patients. Comparison of two groups of patients P <0.05, indicating that the difference was statistically significant. Conclusion Da-Ying-35 treatment of adolescent dysfunctional uterine bleeding with significant side effects, should be promoted in clinical practice.