典型的多发性脱髓鞘病或多发性硬化通过临床表现和影像学特征即可明确诊断,无需组织病理学证实。临床表现类似肿瘤者多见于年轻女性,其组织学特点为髓鞘缺失和相对轴索保留,病灶边缘由于脑实质和血管周围淋巴细胞浸润(图1)、单核细胞和(或)巨噬细胞,以及星形胶质细胞混杂而呈现细胞丰富(图2),而且可以观察到髓鞘碎片被巨噬细胞吞噬现象,提示髓 A typical multiple demyelinating disease or multiple sclerosis can be clearly diagnosed by clinical manifestations and imaging features without histopathological confirmation. Similar to the clinical manifestations of tumor more common in young women, the histological features of myelin loss and relative axial retention, the edge of the lesion due to brain parenchymal and perivascular lymphocyte infiltration (Figure 1), monocytes and (or) macrophages , As well as the astrocytes showed abundant cells (Fig. 2), and the phagocytosis of myelin debris by macrophages was observed, suggesting that the myeloid