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有关青春期的激素改变已有很多资料,但对青春期发育过程的机理仍然了解得很少.在女性中,青春期的发育引向初潮,第一次月经周期常是不规律的和无排卵的.这样的周期是否反映了未成熟垂体对促性腺激素释放激素(GnRH)的反应与卵巢类固醇分泌之间的关系?本文对此进行了研究.选择90例健康少女,测定初潮后5年内血浆雌二醇(E_2)和孕酮(P)基础值以及促黄体生成激素(LH)和促卵泡成熟激素(FSH)对GnRH的反应,以了解初潮后女孩的成熟过程.此组少女年龄12～19岁,平均初潮年龄为13岁9个月.妇科年龄(初潮后时间)6个月至5年.对照组为23
There are a lot of information on the hormonal changes of puberty, but little is known about the mechanism of puberty. In women, adolescent development leads to menarche and the first menstrual cycle is often irregular and anovulatory. Of the cycle reflects the relationship between the response of immature pituitary gonadotropin-releasing hormone (GnRH) and ovarian steroid secretion? This article was studied.Select 90 healthy girls, measured within 5 years after menarche plasma estradiol (E_2) and progesterone (P) basal values and the response of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to GnRH in order to understand the maturation process of girls after menarche.The girls were 12 to 19 years old, The mean menarche age was 13 years and 9 months, and the gynecologic age (after menarche) was 6 months to 5 years. The control group was 23