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发病机理肺泡炎:主要发病机理是各种类型细胞增多造成的炎症。很象T淋巴细胞引起的慢性炎症过程。另一方面,肺泡巨噬细胞和嗜中性白细胞引起随发的损伤的纤维化,而嗜酸性细胞和嗜硷性细胞/肥大细胞可能也引起损伤,但程度较轻。肺泡巨噬细胞是炎症的主要细胞,对损伤和修复起重要作用。它在局部增殖的速度为其正常的3—4倍。肺泡巨噬细胞释放:(1)对嗜中性白细胞的化学吸引剂;(2)氧化剂,直接损伤肺实质,特别是上皮细胞。(3)肺间质细胞的多种生长信息。嗜中性白
Pathogenesis Alveolitis: The main pathogenesis is caused by various types of cells caused by inflammation. Much like the chronic inflammatory process caused by T lymphocytes. On the other hand, alveolar macrophages and neutrophils cause fibrosis of the lesion while eosinophils and basophils / mast cells may also cause damage but to a lesser extent. Alveolar macrophages are the major inflammatory cells that play an important role in injury and repair. It proliferates at a local rate of 3-4 times normal. Alveolar macrophages release: (1) chemical attractant to neutrophils; (2) oxidant, which directly damages the lung parenchyma, especially the epithelial cells. (3) a variety of lung interstitial growth information. Neutrophil