自发现肾素迄今已八十余年,但直至近十余年,人们才认识到肾外存在肾素。此外,血浆及其它组织提取物中尚有无活性肾素。有人认为后者可能是活性型肾素的前体,但其生理作用以及与活性型肾素间的关系均未阐明。本文探讨了常用的体外激活无活性肾素的方法,并观察了正常人和高血压患者血浆无活性肾素的浓度以及氯化钠对高血压患者血浆总肾素和无活性肾素的影响。 Since the discovery of renin has been more than eighty years, but until nearly ten years, people realized that renin exists outside the kidney. In addition, plasma and other tissue extracts still have no active renin. Some people think that the latter may be a precursor of active renin, but its physiological role and the relationship between active renin are not elucidated. This article discusses the commonly used in vitro activation of inactive renin method, and observed in normal subjects and patients with hypertension plasma renin non-active concentration and sodium chloride on plasma total renin and inactive renin effects.