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目的探讨产前子痫患者颅脑临床及影像学表现。方法分析12例产前子痫的临床资料。结果 12例产前子痫中,主要临床表现为嗜睡与昏睡、昏迷、视力障碍、癫痫发作、记忆力与注意力下降、共济失调、偏瘫及颅内压增高。神经影像学以可逆性白质异常病变为特征,多数位于半球后部白质、脑干、丘脑,部分病例出现顶枕叶点、片状出血。结论产前子痫可引起后部白质脑病,其病变主要位于后部白质,部分位于侧脑室旁、小脑白质与脑干,经过正确的治疗,大部分患者的症状、体征及神经影像学改变可恢复到病前水平,部分病例出现不可逆性梗死与出血。
Objective To investigate the clinical manifestations and imaging features of preeclampsia patients. Methods The clinical data of 12 preeclampsia were analyzed. Results Among the 12 preeclampsia patients, the main clinical manifestations were drowsiness and lethargy, coma, visual impairment, seizures, decreased memory and attention, ataxia, hemiplegia and increased intracranial pressure. Neuroimaging is characterized by reversible white matter abnormalities, most of which are located in the posterior white matter, brainstem, and thalamus in the hemisphere. In some cases, the top occipital lobe and flake bleed appear. Conclusions Pre-eclampsia can cause posterior white matter encephalopathy. The lesion is mainly located in the posterior white matter, partly in the lateral ventricle, white matter of the cerebellum and brain stem. After proper treatment, most patients’ symptoms, signs and neuroimaging changes may be Return to the pre-sick level, some cases of irreversible infarction and bleeding.