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目的：探讨机体体液免疫在花斑癣发病中的作用和意义。方法：以糠秕马拉色菌（M．furfur）整菌（WMF）为抗原，用间接酶联免疫吸附试验（ELISA）方法，检测68例花斑癣患者和41例正常人血清中的抗WMF抗体。结果：正常人血清中存在高滴度的抗WMF抗体，花斑癣患者血清中抗WMFIgG抗体明显低于正常对照组（P＜0．01），男性患者血清中IgG抗体低于女性患者（P＜0．01），病程1年以上者血清中特异的IgG抗体低于病程不到1年者（P＜0．01）。结论：机体血清抗M．furfur抗体可能是人体内天然抗体，且特异的IgG抗体具有保护作用。支持花斑癣的发病与免疫缺陷有关。
Objective: To explore the role and significance of body fluid immunity in the pathogenesis of tinea versicolor. Methods: The anti-WMF activity in serum of 68 cases of Pityriometrics and 41 normal persons was detected by indirect enzyme-linked immunosorbent assay (ELISA) using M.furfur whole strain (WMF) as antigen. antibody. Results: The serum levels of anti-WMF antibody were high in normal people. The serum levels of anti-WMFIgG antibody in tinea versicolor were significantly lower than those in normal controls (P <0.01). The serum levels of IgG antibodies in male patients were lower than those in women <0.01). Patients with more than one year of duration had lower specific IgG antibodies than those less than 1 year (P <0.01). Conclusion: The body serum anti-M Furfur antibodies may be natural antibodies in the human body, and specific IgG antibodies have a protective effect. Support the incidence of pityriasis and immunodeficiency.