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目的:探讨低分子肝素(Low molecular weight heparin,LMWH)在老年急性冠脉综合征(Acute coronary syndrome,ACS)中的治疗效果。方法:将我院老年病房96例老年ACS患者分为A、B2组,2组在年龄、性别、合并症上无显著差异(P>0.05),A组应用长效硝酸酯类、β受体阻滞剂、ACEI类药物和拜阿司匹林及他丁类调脂药物治疗,B组在A组治疗的基础上加用LMWH。疗程均为l周,观察LMWH治疗老年ACS的疗效和安全性。结果:在治疗过程中,B组临床症状及心电图的改善均优于A组,2组间比较有显著性差异(P<0.05),2组均无严重出血不良反应。结论:LMWH治疗老年ACS安全有效,并对愈后有积极的影响。
Objective: To investigate the therapeutic effect of low molecular weight heparin (LMWH) in elderly acute coronary syndrome (ACS). Methods: A total of 96 elderly ACS patients were divided into A and B2 groups. There were no significant differences in age, sex and comorbidity between the two groups (P> 0.05). In group A, long-acting nitrates, Blockers, ACEIs, aspirin, and statins, and group B was given LMWH on the basis of group A treatment. The course of treatment were l weeks, observe the efficacy and safety of LMWH in the treatment of elderly ACS. Results: During the course of treatment, the improvement of clinical symptoms and electrocardiogram in group B were better than that of group A. There was a significant difference between the two groups (P <0.05). There was no serious bleeding adverse reaction in both groups. Conclusions: LMWH is safe and effective in the treatment of elderly ACS and has a positive effect on prognosis.