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目的探讨环氧乙烷急性中毒的临床特点,提高环氧乙烷急性中毒的防治水平。方法回顾性分析3例急性环氧乙烷中毒患者的主要临床表现,以及该毒物对机体各脏器功能的损害特征。结果环氧乙烷泄漏后可经呼吸道吸收引起急性中毒,3例中毒患者均出现神经系统功能受抑制症状,其中2例出现攻击行为、精神错乱等异常症状;此外,急性环氧乙烷中毒可出现全身多脏器功能不同程度损伤。结论急性环氧乙烷中毒治疗目前尚无特效解毒剂。经采取综合有效的对症和支持治疗措施,3例患者均痊愈出院,预后良好。
Objective To investigate the clinical characteristics of ethylene oxide acute poisoning and improve the prevention and treatment of ethylene oxide acute poisoning. Methods The clinical manifestations of 3 patients with acute ethylene oxide poisoning were retrospectively analyzed, and the damage characteristics of the poison to various organ functions of the body were retrospectively analyzed. Results After the leakage of ethylene oxide, it could be acutely poisoned through the respiratory tract. In all 3 cases of poisoning, the symptoms of nervous system function were inhibited. Among them, 2 cases showed abnormal symptoms such as aggressive behavior and insanity. In addition, acute ethylene oxide poisoning Multiple organ function appears to varying degrees of injury. Conclusions Acute ethylene oxide poisoning is currently no effective antidote. After a comprehensive and effective symptomatic and supportive treatment measures, 3 patients were discharged and discharged with good prognosis.