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自1977年阴离子隙(AG)用作判断酸碱失衡以来,临床上首先出现了混合性代谢性酸中毒,即高AG代谢酸中毒(代酸)合并高氯代酸。1981年Narins等应用单纯性酸碱失衡预计代偿公式。作为判断单纯性或二重酸碱失衡的依据。二重酸碱失衡中以代酸合并代谢性碱中毒(代碱)的代偿机理比较复杂,分高AG代酸合并代碱和正常AG代酸合并代碱。如在代酸合并代碱的基础上,又出现呼吸性酸碱失衡时,称三重酸碱失衡(TABD)分呼
Since anion gap (AG) was used to determine the acid-base imbalance in 1977, mixed metabolic acidosis first appeared in clinic, that is, high AG metabolic acidosis (acid) combined with high chlorinated acid. In 1981, Narins et al estimated the compensatory formula of simple acid-base imbalance. As a basis for judging simple or double acid-base imbalance. Double acid-base imbalance in the metabolic acidosis associated with metabolic alkalosis (generation of base) compensation mechanism is more complicated, divided into high-AG acid generation on behalf of the base and normal AG acid generation on behalf of the base. As in the generation of acid and alkali on the basis of the merger, and respiratory acid-base imbalance occurs, the triple acid-base imbalance (TABD) call