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目的对高血压用药情况进行分析,为临床合理治疗提供依据。方法采用WHO推荐的用药种类、用药频率(DDDs)、药物利用指数(DUI)、联合用药和医学统计等方法。对武汉市汉口医院从2010年1月至2011年1月门诊处方中降血压药物的应用情况进行回顾性调查分析。结果 252例门诊降血压药DDDs排序前3位的药品分别是苯磺酸氨氯地平、复方利血平氨苯蝶啶片、美托洛尔,大部分药物的DUI值接近于1,联合用药率达20.33%,以钙拮抗剂与β受体阻滞药联用最多。结论本调查显示各类药物使用基本趋于合理,但还需加强对高血压患者关于用药知识培训及对血压控制重视方面的宣传;同时,在临床应用中,根据患者的实际情况,合理选择疗效可靠。不良反应少、经济适用的降压药物能有效降低高血压患者并发症的发症率,改善高血压患者的生活质量。
Objective To analyze the situation of hypertension medication and provide the basis for clinical rational treatment. Methods According to the types of drugs recommended by the WHO, frequency of medication (DDDs), drug utilization index (DUI), combination medication and medical statistics. Wuhan Hankou Hospital from January 2010 to January 2011 in outpatient prescriptions of antihypertensive drugs in the application of retrospective investigation and analysis. Results The top three DDDs of outpatient antihypertensive drugs were amlodipine besylate, trimethoprim compound tablets and metoprolol. The DUI value of most drugs was close to 1, and the combination therapy Rate of 20.33%, with calcium antagonists and beta blockers combined with the most. Conclusion The survey shows that the use of various drugs tend to be reasonable, but the need to strengthen the knowledge about hypertension in patients with training and knowledge of blood pressure control aspects of publicity; the same time, in clinical practice, according to the actual situation of patients, a reasonable choice of efficacy reliable. Adverse reactions, less cost-effective antihypertensive drugs can effectively reduce the incidence of complications in hypertensive patients, improve the quality of life of hypertensive patients.