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为了探讨甲状腺激素对机体β-内啡肽(β-EP)水平的影响,本文通过对42例Graves病人外周血β-EP测定表明,甲亢治疗前和治疗后恢复时β-EP较对照组呈非常显著和显著增高,使用维持剂量时降至正常。此外,病程在3个月内也有显著增高,以后无显著变化。分析结果认为,甲亢也是一个应激过程,ACTH和β-EP在垂体存在着共同分泌机制,它们与应激和其他刺激呈平行变化。这些变化是甲状腺激素自身作用的结果。
In order to investigate the effect of thyroid hormones on the level of β-endorphin (β-EP), the β-EP in peripheral blood of 42 patients with Graves showed that β-EP before and after treatment of hyperthyroidism was higher than that of the control group Very significant and significantly higher, using the maintenance dose to normal. In addition, the course of disease was also significantly increased within 3 months, no significant change after. The results showed that hyperthyroidism is also a stress process, ACTH and β-EP exist in the common pituitary secretion mechanism, they and stress and other stimuli were parallel changes. These changes are the result of thyroid hormone itself.