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目的探讨妥洛特罗贴剂在咳嗽变异性哮喘儿童治疗中的作用。方法将郑州市儿童医院哮喘门诊确诊为咳嗽变异性哮喘患儿随机分为两组,治疗组与对照组各30例,对照组常规治疗(口服孟鲁司特及抗组胺药物),治疗组除以上常规治疗外每晚应用妥洛特罗贴剂经皮给药,比较两组患儿咳嗽缓解的时间及1周肺功能改善情况。结果应用妥洛特罗贴剂的患儿咳嗽缓解时间及1周肺功能改善情况明显短于对照组,差异有统计学意义(P<0.05)。结论妥洛特罗贴剂在缩短咳嗽时间方面起效快,1周肺功能情况改善明显,临床疗效显著。
Objective To investigate the effect of tulobuterol in the treatment of children with cough variant asthma. Methods Children with asthma at Zhengzhou Children’s Hospital were randomly divided into two groups: control group (30 cases) and control group (conventional montelukast and antihistamine group), treatment group In addition to the above routine treatment of each application of epothilone patch transdermal delivery, the two groups of children with cough relief time and 1 week lung function improvement. Results The improvement of cough relief time and improvement of pulmonary function in 1 week in the children treated with tulobuterol patch was significantly shorter than that in the control group (P <0.05). Conclusion The use of tulobuterol patch in the shortening of cough time, rapid onset, one week of significant improvement in lung function, clinical efficacy was significant.