【摘 要】
：
目的 对比分析家族性痛风和散发痛风患者临床资料,为痛风的早期治疗及预后判断提供依据.方法 收集家族性痛风431例和散发病风1899例,比较其临床特征及生化特点.采用t检验和x2
【机 构】
：
青岛大学医学院附属医院痛风病实验室
论文部分内容阅读
目的 对比分析家族性痛风和散发痛风患者临床资料,为痛风的早期治疗及预后判断提供依据.方法 收集家族性痛风431例和散发病风1899例,比较其临床特征及生化特点.采用t检验和x2检验进行统计分析.结果 ①家族性痛风组初发年龄(44±14)岁、发作时血尿酸浓度(456±118) μmol/L均显著低于散发痛风组[分别为(47±13)岁,(472±125)μmol/L,P＜0.05)].②家族性痛风组患者 中高嘌呤饮食(67.7％和88.2％)、饮酒(31.3％和44.5％)及首发累及第一跖趾关节所占比例(69.1％和77.4％)明显低于散发痛风患者(P＜0.05),而女性患者(9.7％和6.6％)、首发累及踝关节(18.1％和11.3％)、无明显诱因(25.2％和2.5％)及并发脂代谢紊乱(77.4％和71.1％)所占比例明显高于散发痛风组(P＜0.05).结论 山东沿海地区家族性痛风患者发病年龄较早,痛风发作时血尿酸水平较低,女性发病概率增加,易并发脂代谢紊乱,且家族成员容易漏诊,需详细追溯家族史,以期做到早期预防和及时治疗.
其他文献
目的探讨胎盘早剥早产儿使用普通肝素防治凝血功能异常的最合理剂量。方法纳入60例胎盘早剥早产儿,随机分为3组,分别给予不同剂量普通肝素。A组用0.1 mg·kg-1普通肝素、B组
The application of human induced oxygen consumption and carbon emission theory in urban region was summed up and on this base a new model of urban carbon and ox
The relationship between the groundwater and the surface eco-environment in arid area is very close. In this paper, the authors extracted normalized difference
In the present study, the relationship between the nutritional status of leaves and the development of symptoms of cotton leaf curl virus (CLCuV) in two cotton
Automated, real-time, and continuous techniques for monitoring suspended sediment concentration in rivers and reservoirs can play an important role in the impro
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7
Cereal aleurone has been established as a model system to investigate giberrellin (GA) and abscisic acid (ABA) responses. Using Barley 1 GeneChip, we examined t
A tuned hybrid-tanks/mass damper (THMD) system is presented in this paper, and the equation of motion of structure-THMD system is formulated. A phasic differenc
nifB-MoFe protein (nifB-Av1), △nifE MoFe protein (△nifE Av1) and △nifZ MoFe protein (△nifZ Av1) were obtained by chromatography on DE52, Sephacryl S-300 and
目的为了鉴定并验证CUL4A-DDB1泛素连接酶复合体中参与DNA损伤修复反应过程的1～2种关键成分在损伤识别、早期及晚期修复中的动态变化,拟构建含有串联亲和纯化(TAP)标签载体并