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恶性黑色素瘤根据病史、临床表现及病理组织学检查诊断,但有不少病例诊断困难。近年对本病用单克隆抗体(McAb)进行研究,并开始应用于诊断和抬疗。作者等曾报道用~(111)In标记抗人黑色素瘤鼠型McAb(ZME-108),可诊断本病。本次用于无黑色素性黑色素瘤的诊断,再次确认此抗体的可用性。报告如下 患者23岁,男性,主诉右后颈部皮下肿物。既往史和家族史无特殊记载。现病史自1987年6月中旬,发现右后颈部姆指大小的皮下肿物。同年7月6日手术切除。但肿瘤复
Malignant melanoma is diagnosed on the basis of medical history, clinical manifestations, and histopathological examinations, but many cases are difficult to diagnose. In recent years, monoclonal antibodies (McAbs) have been investigated for this disease and have begun to be used for diagnosis and treatment. The authors have reported the use of ~(111)In labeled anti-human melanoma murine McAb (ZME-108) to diagnose this disease. This was used for the diagnosis of amelanotic melanoma, and once again confirmed the availability of this antibody. The report is as follows: The patient was 23 years old and the man complained of a subcutaneous tumor in the right posterior neck. Past history and family history have no special record. History of the disease Since mid-June 1987, a subcutaneous mass with the size of the right posterior neck was found. On July 6 of the same year, surgical resection was performed. But the tumor complex