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本草基因组计划(HerbGP)是针对具有重大经济价值和典型次生代谢途径的药用植物进行的全基因组测序和后基因组学研究的系列计划。本文从物种选择,全基因组测序、组装和生物信息学分析,后基因组研究等方面系统阐述了本草基因组计划的研究策略。该计划将推动一批具有典型次生代谢途径的模式植物研究平台的建立,促进各种“组学”研究方法在药用植物研究领域中的应用,推动中国传统药学进入生命科学研究前沿领域。本草基因组计划为占领中药基础研究领域的科技制高点提供了难得的机遇,还将通过对药用植物有效成分生物合成路径的解析和药用植物优良品种的选育对我国天然药物的研发和中药农业的发展产生巨大而深远的影响。
HerbGP (HerbGP) is a series of programs for genome-wide sequencing and post-genomics research on medicinal plants with significant economic value and typical secondary metabolic pathways. This article systematically expounds the research strategy of GenBank in terms of species selection, genome-wide sequencing, assembly and bioinformatics analysis and post-genome research. The program will promote the establishment of a group of model plant research platforms with typical secondary metabolic pathways and promote the application of various research methods in the field of medicinal plants and promote the entry of traditional Chinese medicines into the frontiers of life science research field. The Herb Genome Project provides a rare opportunity for occupying the commanding height of science and technology in the basic research of traditional Chinese medicine. Through the analysis of biosynthetic pathways of active ingredients in medicinal plants and the breeding of elite varieties of medicinal plants, the research and development of natural medicine and Chinese medicine agriculture The development has a huge and far-reaching impact.