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目的了解近年来不同性别及不同年龄段大肠癌临床及病理等特点。方法回顾性调查我院2005年1月~2010年3月共1797例经病理确诊的大肠癌患者,统计其年龄、性别、城乡分布及癌肿部位、病理类型等。结果大肠癌发病呈老年化趋势,大于40岁的中老年组占绝大多数,达到92.7%,青年组仅占7.3%;不同性别及不同年龄段的各部位结肠癌发生率构成比无显著性差异,P>0.01;不同性别组的大肠癌病理特点无显著性差异,青年患者中黏液腺癌和印戒细胞癌所占比例较高,有统计学差异(P<0.01);直肠癌仍是原发性结直肠癌最常见的部位,腺癌是最常见的病理类型。结论通过对大肠癌的临床及病理特点的研究,揭示其发病及诊断的依据,有助于医务人员建立合理的治疗体系,帮助患者治愈疾病。
Objective To understand the clinical and pathological characteristics of colorectal cancer of different genders and ages in recent years. Methods Retrospective survey of 1797 cases of pathologically confirmed colorectal cancer patients from January 2005 to March 2010 in our hospital were retrospectively studied. The age, gender, distribution of urban and rural areas, tumor sites and pathological types were calculated. Results The incidence of colorectal cancer showed an aging trend. The majority of middle-aged and older patients over 40 years old reached 92.7%, while the young group only accounted for 7.3%. There was no significant difference in the incidence of colon cancer between different sexes and different age groups (P <0.01). There was no significant difference in the pathological features of colorectal cancer in different sex groups. The proportion of mucinous adenocarcinoma and signet-ring cell carcinoma was higher in young patients (P <0.01), while the rectal cancer was still The most common site of primary colorectal cancer, adenocarcinoma is the most common pathological type. Conclusion The study of clinical and pathological features of colorectal cancer reveals the basis of its pathogenesis and diagnosis and helps medical staff to establish a reasonable treatment system to help patients cure the disease.