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目的探讨儿童消化道疾病的胃镜下表现及与幽门螺杆菌(Hp)的相关性。方法选择2430例消化道疾病患儿进行胃镜检查,其中2025例行胃黏膜快速尿素酶检测,1892例行胃黏膜病理学检查,并进行系统分析。结果2430例患儿中检出病变2043例(84.1%),其中浅表性胃炎1014例(41.7%),十二指肠炎355例(14.6%),浅表性胃炎合并十二指肠炎302例(12.4%),十二指肠球部溃疡254例(10.5%),胃溃疡47例(1.9%),食管及(或)胃底静脉曲张23例(0.9%),食管炎14例(0.58%),苍白胃粘膜10例(0.4%),息肉3例(0.1%),异物9例(0.4%),幽门梗阻3例(0.1%),贲门痉挛、幽门痉挛各1例;2025例快速尿素酶检测中Hp阳性731例;1892例病理学检查中Hp阳性1047例。Hp阳性主要疾病分别为十二指肠球部溃疡171例(171/232),胃溃疡24例(24/41),浅表性胃炎317例(317/963),十二指肠炎101例(101/369),浅表性胃炎合并十二指肠炎99例(99/275)。结论胃镜检查对诊断小儿消化道疾病具有重要意义。
Objective To investigate the gastroscopic performance of children with gastrointestinal diseases and its relationship with Helicobacter pylori (Hp). Methods A total of 2430 children with gastrointestinal diseases were enrolled in this study. Gastric endoscopy was performed in 2025 patients with gastric mucosal rapid urease and 1892 gastric mucosal pathological examination. Results A total of 2043 cases (84.1%) were detected in 2430 children, including 1014 cases (41.7%) of superficial gastritis, 355 cases (14.6%) of superficial gastroenteritis, 302 cases of superficial gastritis complicated with duodenitis (12.4%), duodenal ulcer in 254 cases (10.5%), gastric ulcer in 47 cases (1.9%), esophageal and / or gastric varices in 23 cases (0.9%) and esophagitis in 14 cases 10% (0.4%) of pale gastric mucosa, 3 cases (0.1%) of polyps, 9 cases (0.4%) of foreign bodies, 3 cases of pyloric obstruction (0.1%), 1 case of cardia spasm and 1 case of pyloric spasm. Hp positive 731 cases of urease test; 1892 cases of pathological examination Hp positive 1047 cases. Hp-positive main diseases were duodenal ulcer in 171 cases (171/232), gastric ulcer in 24 cases (24/41), superficial gastritis in 317 cases (317/963), and duodenitis in 101 cases ( 101/369), superficial gastritis with duodenitis in 99 cases (99/275). Conclusion Gastroscopy is important for the diagnosis of children with gastrointestinal diseases.