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目的观察前部视网膜冷凝术(anteriorretinalcryotherapy,ARC)对开角型新生血管性青光眼及ARC联合小梁切除术对闭角型新生血管性青光眼的疗效。方法对11例(12只眼)开角型新生血管性青光眼单独行ARC,22例(22只眼)闭角型新生血管性青光眼行ARC联合小梁切除术;另选31例(32只眼)闭角型新生血管性青光眼单独行ARC或睫状体冷凝术作对照。随访6~26个月。结果单独行ARC可使92%(11/12)的开角型新生血管性青光眼眼压恢复正常,虹膜新生血管消退,与单独行ARC的闭角型新生血管性青光眼比较,差异有显著性(P<0.05)。对闭角型新生血管性青光眼,行ARC联合小梁切除术,可使86%(19/22)的患者眼压恢复正常,虹膜新生血管消退,明显优于仅行ARC或睫状体冷凝术者(P<0.01)。此联合术式可使90%(18/20)的患者眼痛消失,67%(8/12)的患者视力保持,与睫状体冷凝术比较,差异有显著性(P<0.05)。结论认为ARC单独应用可治疗早期新生血管性青光眼,晚期患者需联合小梁切除术治疗。
Objective To observe the effect of anteriorretinal cryotherapy (ARC) on angle-closure neovascular glaucoma (OPV) and open-angle neovascular glaucoma (ARC) combined with trabeculectomy. Methods Eleven patients (12 eyes) with open angle neovascular glaucoma were treated with ARC and 22 cases (22 eyes) with angle closure neovascular glaucoma under ARC combined with trabeculectomy. The other 31 patients (32 eyes) ) Angle closure neovascular glaucoma alone ARC or ciliary body condensation as a control. Follow-up 6 to 26 months. Results ARC alone could restore the IOP of 92% (11/12) open-angle neovascular glaucoma and iris neovascularization, which was significantly different from that of ARC alone P <0.05). In the angle-closure neovascular glaucoma, ARC combined with trabeculectomy can restore the intraocular pressure to 86% (19/22) and the iris neovascularization, which is better than ARC or ciliary body condensation (P <0.01). This combined procedure resulted in the disappearance of eye pain in 90% (18/20) of patients and in 67% (8/12) of patients, which was significantly different from that of ciliary body condensation (P <0.05) . Conclusions that ARC alone can treat early neovascular glaucoma, advanced patients need to be treated with trabeculectomy.