胰腺癌(PC)为致死性最高的恶性肿瘤之一,居美国肿瘤相关死亡的第四位[1],患者5年生存率仅为3%,中位生存期约为5~6个月[2]。在中国,胰腺癌发病率呈稳步增长。据统计上海从1972~1974到1993~1994之间,胰腺癌发病率增长了40%~50%[3]。胰腺癌患者早期缺乏特异性的临床表现,确诊时已到晚期,仅有约10%~20%的患者能行手术根治,术后患者 Pancreatic cancer (PC) is one of the most lethal malignant tumors in the United States, ranking fourth in the country for cancer-related deaths [1]. The 5-year survival rate is only 3% and the median survival time is about 5-6 months [ 2]. In China, the incidence of pancreatic cancer showed a steady increase. According to statistics, from 1972 ~ 1974 to 1993 ~ 1994 in Shanghai, the incidence of pancreatic cancer increased by 40% to 50% [3]. Early pancreatic cancer patients lack specific clinical manifestations, when the diagnosis is late, only about 10% to 20% of patients underwent radical surgery, postoperative patients