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目的:探讨在急性髓系白血病(AML)伴急性肿瘤溶解综合征(ATLS)患者治疗和预防中的疗效。方法:选择60例AML伴不同程度ATLS的患者,随机分为治疗组和对照组,每组各30例,治疗组在对照组治疗基础上加用复方丹参注射液,分别观察两组疗效及有关指标。结果:治疗组ATLS的发生率明显低于对照组,治疗组中已经发生ATLS的较对照组症状轻,且不良反应轻微;治疗组血小板(PLT)、凝血功能(PT、APTT)较对照组无明显差异。结论:复方丹参注射液在AML伴ATLS患者治疗和预防中的疗效肯定,副作用小,且很经济。
Objective: To investigate the therapeutic effect in the treatment and prevention of acute myeloid leukemia (AML) with acute tumor lysis syndrome (ATLS). Methods: Sixty patients with AML with different degree of ATLS were randomly divided into treatment group and control group, with 30 cases in each group. The treatment group was given compound Danshen injection on the basis of the control group, and the curative effect and the correlation between the two groups were observed index. Results: The incidence of ATLS in the treatment group was significantly lower than that in the control group. The ATLS in the treatment group was lighter than the control group with mild adverse reactions. The platelet (PLT), coagulation function (PT, APTT) Significant differences. Conclusion: The efficacy of compound Danshen injection in the treatment and prevention of AML patients with ATLS is definite, the side effects are small, and it is economical.