川芎嗪和芍药甙是十全大补丸中的主要有效成分。本文用毛细管区带电泳法分离测定了这两种成分。以40mmol/L硼砂（含3％乙醇，V／V）、pH10．88为电泳介质，未涂层熔融硅毛细管，压力进样（69kPa·s），15kV恒压电泳（23℃），检测波长232nm。在20～700mg/L和15～55mg／L范围内，川芎嗪与芍药甙可分别定量分析。加样回收率川芎嗪为101．0％±1．8％，芍药甙为99．3％±2．0％。 Ligustrazine and paeoniflorin are the main active ingredients in Shiquan Dabu pills. In this paper, capillary zone electrophoresis was used to separate the two components. Electrophoretic medium, uncoated fused silica capillary, pressure injection (69 kPa · s), 15 kV constant voltage electrophoresis (23 ℃) with 40 mmol / L borax (containing 3% ethanol and V / V) 232nm. In the range of 20 ~ 700mg / L and 15 ~ 55mg / L, tetramethylpyrazine and paeoniflorin can be quantitatively analyzed. The recoveries of ligustrazine were 101.0% ± 1.8% and paeoniflorin was 99.3% ± 2.0%.