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目的:探讨妊娠早期人微小病毒B19感染对孕妇血液系统的影响。方法:用酶联免疫吸附试验(ELISA)法检测60例早期自然流产患者(观察组)及同期自愿人工流产的健康早孕妇女60例(对照组)血清中HPVB19-Ig M的含量,检测两组孕妇血红蛋白、红细胞、白细胞及血小板计数并进行比较。结果:观察组、对照组人HPVB19-Ig M阳性患者血红蛋白和红细胞计数均低于阴性患者,差异有统计学意义(均P<0.05);观察组B19感染孕妇中贫血患病率53.85%(7/13)高于对照组21.28%(10/47),差异有统计学意义(P<0.05)。结论:人微小病毒B19感染对红细胞影响较明显,是病毒感染孕妇贫血的重要原因。
Objective: To investigate the influence of infection of human parvovirus B19 on the blood system of pregnant women in early pregnancy. Methods: The serum levels of HPVB19-IgM in 60 patients with early spontaneous abortion (observation group) and 60 healthy pregnant women (control group) in the spontaneous abortion of the same period were detected by enzyme linked immunosorbent assay (ELISA) Pregnant women with hemoglobin, red blood cells, white blood cells and platelet count and compared. Results: The hemoglobin and erythrocyte count in observation group and control group were lower than those in negative group (P <0.05). The prevalence of anemia in observation group was 53.85% (7) / 13) higher than the control group 21.28% (10/47), the difference was statistically significant (P <0.05). Conclusion: The infection of human parvovirus B19 on erythrocytes is more obvious, which is an important cause of anemia in pregnant women infected with virus.