对钢铁企业 115 2名不同噪声暴露剂量职工、 2 88名低噪声暴露 (对照 )人群的血脂水平及其相关因素进行了流行病学研究。结果表明 :高胆固醇血症发生率明显随噪声暴露剂量的增加而增高 ,有统计学意义 (P <0 0 5 )。多元Logistic回归证实 ,在调整了年龄、饮酒、肥胖等可能的混杂因素干扰后 ,累积噪声暴露量的OR =1 0 2 2 ,P =0 0 33。提示累积噪声暴露量是高胆固醇血症的危险因素 ,二者存在剂量 -反应关系。体重指数、年龄、饮酒也是血清高胆固醇的危险因素。噪声暴露是引起工人血清胆固醇升高的原因之一 Epidemiological studies on blood lipid levels and related factors in 1152 workers with different noise exposure levels and 2 88 low noise exposure (control) groups in the iron and steel industry were conducted. The results showed that: the incidence of hypercholesterolemia significantly increased with the increase of noise exposure dose, with statistical significance (P <0 05). Multivariate Logistic regression confirmed that after adjusting for possible confounding factors such as age, drinking, and obesity, the cumulative noise exposure was OR = 1022, P = 0 033. Tip cumulative noise exposure is a risk factor for hypercholesterolemia, the two dose-response relationship. Body mass index, age, alcohol consumption are also risk factors for serum high cholesterol. Noise exposure is one of the causes of elevated serum cholesterol in workers