硝苯吡啶是一种有效的钙离子抑制剂。目前被广泛应用于治疗心血管疾病,其中用它治疗原发性高血压病,更受到人们的重视。我们对66例原发性高血压病人进行了观察,在口服硝苯吡啶前后对血压、血浆血管紧张素Ⅱ(ATⅡ)、血管紧张素Ⅲ(ATⅡ)及红细胞钠钾等变化进行了分析。现报导如下: 观察对象均系北京酒仙桥心血管病防治区的病人。依照1979年郑州会议标准确诊,男性36例,女性30例。平均年龄46岁。Ⅰ期高血压28例,Ⅱ期高血压38例。平均病程11.8年(范围1-30年)。于服用硝苯吡啶两周前停服其他降压药,女性育龄病人须停服避孕药一个月后再服用硝苯吡啶。服法每日三次,每次10-20毫克。于服药后两周,观察患者血压(上卜 Nifedipine is a potent calcium-ion inhibitor. Currently being widely used in the treatment of cardiovascular disease, which used to treat essential hypertension, more people’s attention. We observed 66 cases of essential hypertension patients before and after oral administration of nifedipine on blood pressure, plasma angiotensin Ⅱ (AT Ⅱ), angiotensin Ⅲ (AT Ⅱ) and sodium erythrocyte sodium and other changes were analyzed. Are reported as follows: The observed objects are Beijing Jiuxianqiao cardiovascular disease prevention and treatment of patients. According to the 1979 meeting in Zhengzhou meeting confirmed, 36 males and 30 females. Average age is 46 years old. Stage I hypertension in 28 cases, stage II hypertension in 38 cases. The average duration of 11.8 years (range 1 - 30 years). In taking nifedipine two weeks ago stopped taking other antihypertensive drugs, women of childbearing age to stop taking contraceptives one month after taking nifedipine. Three times a day, 10-20 mg each time. Two weeks after taking the medicine, the patients’ blood pressure was observed (Shangbu