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目的观察老年反流性食管炎患者应用莫沙必利与埃索美拉唑联合治疗的临床效果。方法选取医院接受治疗的老年反流性食管炎患者88例作为研究对象,按照入院时间先后依次编号,双号为对照组,单号为观察组,每组44例。对照组给予莫必沙利治疗,观察组在对照组基础上应用埃索美拉唑进行治疗,观察2组患者临床疗效及临床症状评分情况。结果观察组总有效率为95.45%,高于对照组的54.55%(P<0.05)。2组患者经治疗后,观察组泛酸、胸骨烧灼感及上腹痛评分均优于对照组(P<0.05)。结论老年反流性食管炎患者应用莫沙必利与埃索米拉唑联合治疗,临床症状显著减轻,提高治疗有效率,临床应用价值较高。
Objective To observe the clinical effect of combined use of mosapride and esomeprazole in elderly patients with reflux esophagitis. Methods Eighty-eight elderly patients with senile reflux esophagitis were enrolled in this study. Patients were followed by admission number, double number as control group and single number as observation group, with 44 cases in each group. The control group was treated with moxibustion, the observation group was treated with esomeprazole on the basis of the control group, and the clinical curative effect and clinical symptom score of the two groups were observed. Results The total effective rate in observation group was 95.45%, which was higher than that in control group (54.55%, P <0.05). Two groups of patients after treatment, the observation group, pantothenic acid, suprasternal soreness and upper abdominal pain scores were better than the control group (P <0.05). Conclusion The combination therapy of mosapride and esopirazole in senile patients with reflux esophagitis significantly reduces the clinical symptoms and improves the treatment efficiency and has higher clinical value.