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目的研究分析丙泊酚用于小儿腹腔镜手术麻醉的临床效果及其安全性。方法选取安阳人民医院2011年5月至2013年5月收治的腹腔镜疝修补术患儿68例,将其按照麻醉方法分为观察组和对照组,对照组使用氯胺酮,观察组使用丙泊酚,对比两组患儿麻醉前(T0)、麻醉诱导后10 min(T1)、手术开始5 min(T2)、手术开始10 min(T3)、手术结束时(T4)、苏醒时(T5)时间点心率和平均动脉压变化情况,同时记录两组患儿苏醒时间及不良反应发生率。结果两组在T1~T5时间点心率和平均动脉压比较差异有统计学意义(P<0.05);且观察组苏醒时间短于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05)。结论给予腹腔镜手术患儿麻醉诱导丙泊酚安全性较高,且不良反应发生率较低,苏醒时间较快,值得临床推广。
Objective To study the clinical effect and safety of propofol in pediatric laparoscopic anesthesia. Methods 68 cases of children with laparoscopic hernia repair who were treated in Anyang People’s Hospital from May 2011 to May 2013 were divided into observation group and control group according to anesthesia method and ketamine in control group. Propofol (T0), 10 min after induction of anesthesia (T1), 5 min after operation (T2), 10 min after operation (T3), T4 (end of operation) Heart rate and mean arterial pressure changes, while recording the recovery time and the incidence of adverse reactions in both groups. Results The heart rate and mean arterial pressure at T1 ~ T5 were significantly different between two groups (P <0.05), and the recovery time in the observation group was shorter than that in the control group (P <0.05). The incidence of adverse reactions in the observation group was lower than that in the control group Group (P <0.05). Conclusion The anesthesia induced propofol in children with laparoscopic surgery is safe, and the incidence of adverse reactions is low, the recovery time is faster, it is worth clinical promotion.