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本文研究发现铅吸收、铅中毒工人血中游离三碘甲状腺原氨酸（ＦＴ＿３）、游离四碘甲状腺原氨酸（ＦＴ－４）、皮质醇含量明显低于对照组工人（Ｆ＜０．０１），且与尿铅、尿δ－ＡＬＡ含量呈明显负相关；铅中毒工人血中ＴＳＨ明显高于对照组工人（Ｐ＜０．０１），且与尿铅、尿δ－ＡＬＡ含量呈明显正相关。结果提示，接铅工人体内铅负荷达铅吸收水平，但尚未产生中毒症状时就已影响了甲状腺、肾上腺皮质的分泌功能，说明某些内分泌腺对铅的损伤作用较敏感，铅损伤某些内分泌腺的功能可能是铅中毒的重要机理之一。
In our study, we found that the levels of free triiodothyronine (FT_3), free tetraethionine (FT-4) and cortisol in blood of lead poisoning workers were significantly lower than those of the control group (P <0.01) ), And had a negative correlation with urinary lead and urinary δ-ALA content. TSH in blood of lead poisoning workers was significantly higher than that of the control group (P <0.01), and the content of δ-ALA in urine lead and urine was significantly positive Related. The results suggest that lead exposure to lead lead uptake of lead in the body, but not yet toxic symptoms have affected the secretion of the thyroid, adrenal cortex, indicating that some of the endocrine glands more sensitive to lead injury, lead damage to some of the endocrine Gland function may be one of the important mechanisms of lead poisoning.