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目的观察米非司酮配伍米索前列醇终止不同孕周中期妊娠（１２～１６周及大于１６～２８周）的效果及安全性，并与利凡诺进行对照比较。方法将无禁忌要求终止妊娠孕妇５６例，其中孕周为１２～１６周（为Ａ组）２７例，＞１６～２８周（为Ｂ组）２９例，Ａ、Ｂ两组中再随机分为米非司酮组（观察组）２８例和利凡诺组（对照组）２８例。观察组给予口服米非司酮５０ｍｇ，每日３次共服两天，总剂量３００ｍｇ，第３天上午服米索前列醇０．６ｍｇ，３小时后，胎儿未排出，加服米索前列醇０．２ｍｇ，以后每小时加服米索前列醇０．２ｍｇ，加至１．２ｍｇ，胎儿未排出为失败。Ｂ组于第５天改用利凡诺羊膜腔内注射引产术。对照组给予已稀雌酚２．０ｍｇ肌注，每日两次，两天后行１００ｍｇ羊膜腔内注射引产术。观察各组引产的成功率，自服米索前列醇或注射利凡诺至宫缩出现的间隔时间（发作时间）、宫缩出现至胎儿排出的间隔时间（排胎时间）及宫缩强度、胎盘残留率及产后出血量。结果Ａ组：观察组引产成功率大于对照组（Ｐ＜０．０５），发作时间及排胎时间明显短于对照组（Ｐ＜０．０１），胎盘残留率低（Ｐ＜０．０１），产后出血量少（Ｐ＜０．０５），宫缩强度弱。而Ｂ组：观察组、对照组间引产成功率、?
Objective To observe the efficacy and safety of mifepristone with misoprostol in terminating different gestational weeks of pregnancy (12-16 weeks and longer than 16-28 weeks), and to compare with Rivanol. Methods 56 cases of pregnant women without contraindication requiring termination of pregnancy were enrolled. Among them, 27 cases were gestational weeks from 12 to 16 weeks (group A), 29 cases from> 16 to 28 weeks (group B) Mifepristone group (observation group) 28 cases and rivanol group (control group) 28 cases. The observation group was given oral mifepristone 50mg, three times a day for a total of two days, a total dose of 300mg, the morning of the third day of misoprostol 0.6mg, 3 hours later, the fetus was not discharged, plus misoprostol 0.2mg, every hour plus misoprostol 0.2mg, add to 1.2mg, the fetus is not discharged as a failure. Group B was switched to rivanol intramuscular injection induction on the fifth day. The control group was given 2.0mg intramuscular injection of diluted estrogen twice daily, two days after 100mg amniotic cavity injection induced abortion. Observe the success rate of induction of labor in each group, self-attendance misoprostol or injection of rivanol to contractions (seizure time), contractions appear to the time of fetal discharge (discharge time) and contractions strength, Placental residual rate and postpartum hemorrhage. Results In group A, the successful rate of induction of labor in the observation group was significantly higher than that in the control group (P <0.05), the time of attack and the time of rowing were significantly shorter than those in the control group (P <0.01) , Less postpartum hemorrhage (P <0.05), weak contractility. While in group B: the success rate of induction of labor between the observation group and the control group?