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目的分析影响２型糖尿病外周神经传导速度的因素，比较合并糖尿病肾病（ＤＮ）与未合并ＤＮ患者的外周神经传导速度的差异。方法检测６３例２型糖尿病患者左正中神经、左腓总神经的运动神经传导速度（分别为ＭＣＶ１、ＭＣＶ２），左正中神经的感觉神经传导速度（ＳＣＶ），同时测定ＦＢＧ、ＨｂＡ１Ｃ和晨尿白蛋白（ＭＡＣ），按ＭＡＣ的水平确定有无ＤＮ并分组，分别统计两组的ＭＣＶ１、ＭＣＶ２、ＳＣＶ。结果ＭＣＶ１、ＭＣＶ２、ＳＣＶ分别与ＨｂＡ１Ｃ、ＭＡＣ水平呈负相关，与年龄无关。ＭＣＶ１、ＭＣＶ２与病程呈负相关。合并ＤＮ者外周神经传导速度较未合并ＤＮ者减慢，两者比较有显著性差异。结论２型糖尿病患者外周神经传导速度与ＨｂＡ１ｃ、ＭＡＣ呈负相关，合并肾脏病变的糖尿病患者常同时合并外周神经病变。
Objective To analyze the factors influencing peripheral nerve conduction velocity in type 2 diabetic patients and compare the difference of peripheral nerve conduction velocity between patients with and without DN. Methods The motor nerve conduction velocity (MCV1, MCV2) and sensory nerve conduction velocity (SCV) of the left median nerve and the left common peroneal nerve of 63 patients with type 2 diabetes mellitus were measured. FBG, HbA1C and morning urine Protein (MAC), according to the level of MAC to determine whether DN and group, respectively, two groups of MCV1, MCV2, SCV. Results MCV1, MCV2 and SCV were negatively correlated with HbA1C and MAC levels, respectively, but not with age. MCV1, MCV2 was negatively correlated with the course of disease. Peripheral nerve conduction velocity in patients with DN was slower than those without DN, the difference was significant. Conclusions Peripheral nerve conduction velocity in patients with type 2 diabetes is negatively correlated with HbA1c and MAC. Patients with diabetic nephropathy often have peripheral neuropathy.