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本文用生长抑素8肽（奥曲肽）、生长抑素14肽（舒得定）、三甘氨酰赖氨酸加压素（可利新）和氨戊酸血管加压素（必压生）等4种进口药物与国产垂体后叶素在食管静脉曲张破裂出血的止血效果、再出血率、并发症、病死率和副反应诸方面进行多中心对照观察。可利新和必压生在3小时和6小时完全止血率略高于另2种生长抑素。但12小时和24小时完全止血率则相似（P＞0．05）。与垂体后叶素相比止血效果明显（p＜0．05）。输血量及副反应亦明显减少。但再出血和存活率方面各组间无明显差别。
In this paper, the somatostatin 8 peptide (octreotide), somatostatin 14 peptide (Shuxuding), three glycyl lysine vasopressin (available new) and valerate vasopressin (will pressure) 4 kinds of imported drugs and domestic pituitrin in esophageal variceal bleeding hemostatic effect, rebleeding rate, complications, mortality and side effects of various aspects of the multicenter control. Can be new and will be pressure at 3 hours and 6 hours completely hemostatic rate slightly higher than the other two somatostatin. However, the complete hemostasis rates at 12 and 24 hours were similar (P> 0.05). Compared with pituitrin hemostatic effect was significantly (p <0.05). Blood transfusion and side effects also significantly reduced. However, there was no significant difference in rebleeding and survival between groups.