本文作者于应用接触X线治疗引起癌的第一例报告后,对Lindelof和Eklund的报告作了补充。作者有机会对该病人连续观察达28年之久,在这期间,病人受过放疗的区域内7次发生光化性角化病和3次以上的鳞状细胞癌(其中一次累及骨质),虽然病人在阳光暴晒下也多次出现光化性角化病,但均未发生在放疗区域内. 另一例为63岁妇女,在接触X线治疗后也出现多个恶性肿瘤。她于1945因患有严重的屈侧型银屑病,累及面部并有严重的脂溢性皮炎而年首次就诊,在几次应用GoecKerman的外涂焦油和蒽林的疗 The authors supplemented Lindelof’s and Eklund’s report after the first report of the treatment of cancer caused by contact with X-rays. The author had the opportunity to continuously observe the patient for a period of 28 years. During this period, the patient had undergone seven actinic keratoses and three or more squamous cell carcinomas (one of which involved bone) within the area undergoing radiotherapy. Although the patient experienced multiple actinic keratoses under sunlight exposure, none of them occurred in the radiotherapy area. Another patient, a 63-year-old woman, developed multiple malignant tumors after exposure to X-rays. She was first treated for the first time in 1945 due to severe psoriasis, facial involvement, and severe seborrheic dermatitis. She was treated with Goec Kerman’s external tar and Yulin for several times.