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目的比较阿奇霉素(AZM)及红霉素(EM)治疗小儿支原体肺炎的疗效观察。方法选取我院2010年5月到2013年5月收治的97例支原体肺炎患儿,在常规对症治疗的基础上,随机分为两组,观察组(n=49)给予阿奇霉素(AMZ)10mg/(kg.d)ivgtt.qd。对照组(n=48)给予EM25mg/(kg.d)ivgtt.qd。其余按肺炎常规治疗比较两组临床疗效,进行统计学分析。结果观察组患儿的疗效明显优于对照组(P<0.05),观察组患儿在临床症状和体征消失时间明显低于对照组(P<0.05)。观察组患儿不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论阿奇霉素静脉滴注治疗儿童支原体肺炎优于红霉素治疗。
Objective To compare the efficacy of azithromycin (AZM) and erythromycin (EM) in the treatment of children with mycoplasma pneumonia. Methods 97 children with mycoplasma pneumonia admitted in our hospital from May 2010 to May 2013 were randomly divided into two groups on the basis of routine symptomatic treatment. The observation group (n = 49) received azithromycin (AMZ) 10 mg / (kg.d) ivgtt.qd. The control group (n = 48) received EM25mg / (kg.d) ivgtt.qd. The rest of the routine treatment of pneumonia compared the clinical efficacy of the two groups for statistical analysis. Results The efficacy of the observation group was significantly better than that of the control group (P <0.05). The clinical symptoms and signs disappeared in the observation group was significantly lower than the control group (P <0.05). The incidence of adverse reactions in observation group was significantly lower than that in control group, the difference was statistically significant (P <0.05). Conclusion Azithromycin intravenous infusion treatment of children with mycoplasma pneumonia than erythromycin treatment.