五维牛磺酸口服液作为维生素补充药物,在临床已应用多年。现行的国家标准未制定活性成份牛磺酸的含量测定方法。牛磺酸结构中不含共轭体系,无法通过普通的UV检测器直接测定。此类物质可通过柱前衍生化引入发色基团后进行检测。我们采用柱前衍生化法,以2,4-二硝基氟苯作衍生化试 Five-dimensional taurine oral solution as a vitamin supplement drugs, has been in clinical use for many years. The current national standard does not develop a method for the determination of taurine content of the active ingredient. The taurine structure does not contain a conjugate system and can not be directly measured by a common UV detector. Such substances can be detected by the introduction of chromophore groups by precolumn derivatization. We use the pre-column derivatization method to 2,4-dinitrofluorobenzene as a derivatization test