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目的探讨慢性纯红细胞再生障碍性贫血(PRCA)的病因、发病机制及治疗方法。方法对我院1998年至2006年收治住院的3例慢性PRCA患者进行血浆置换联合药物治疗,并对其临床资料进行回顾性分析。结果慢性PRCA病因复杂,骨髓象有诊断意义,应用血浆置换联合药物治疗后,血红蛋白和网织红细胞明显提高。结论血浆置换联合药物治疗慢性纯红再障有良好的治疗效果。
Objective To investigate the etiology, pathogenesis and treatment of chronic pure red cell aplastic anemia (PRCA). Methods Three patients with chronic PRCA admitted to our hospital from 1998 to 2006 were treated with plasma exchange and drug therapy. The clinical data were retrospectively analyzed. Results The cause of chronic PRCA was complicated. The diagnosis of bone marrow was of diagnostic significance. The hemoglobin and reticulocyte were significantly increased after plasma exchange combined with drug treatment. Conclusion Plasma exchange combined with drug treatment of chronic pure red aplastic anemia has a good therapeutic effect.