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头颈部恶性肿瘤占全身肿瘤的5%，发病率居第6位，其中，大于90%为鳞状细胞癌[1]。吸烟、酒精及HPV感染是头颈部恶性肿瘤发病相关的最重要因素[2]。头颈部恶性肿瘤具有较高的颈淋巴结转移率，而有关颈部VI区淋巴结转移的研究较少。本论文就目前国内外关于颈部VI区淋巴结在头颈部恶性肿瘤中意义的研究做一综述。作者分别就VI区淋巴结中各个区域淋巴结在头颈部恶性肿瘤中的意义做一阐述。“,”At present, head and neck cancer is still one of the most common tumors, it is located in the sixth, accounting for 5% of all tumors. Head and neck squamous cell carcinoma which accounts for more than 90%[1]. Smoking, alcohol and HPV infections are some of the most important factors that lead to head and neck cancer [2]. Head and neck cancer have a higher rate of lymph node metastasis, and there lack the significance study that how the level VI lymph nodes in head and neck carcinoma influence its diagnosis and prognosis. This paper summarizes the significance study of domestic and abroad about the level VI lymph nodes on the head and neck tumors.