库兴氏病(增生型皮质醇增多症)以往多采用肾上腺切除术和垂体放疗或二者联合治疗,疗效并非十分满意。近几年来,国外屡有报导应用5-羟色胺(简称5-HT)拮抗剂——赛庚啶(Cyproheptadine,又名Periactin)治疗者,国内有关报导尚少,我们从1979年11月起对8例库兴氏病作了治疗观察,取得较满意的效果,总结分析如下: Cushing’s disease (hyperplasia of hyperplastic cortisol) used to use adrenalectomy and pituitary radiotherapy or a combination of the two in the past, the efficacy is not very satisfactory. In recent years, there have been reports of the use of 5-hydroxytryptamine (abbreviated as 5-HT) antagonists, Cyproheptadine (also known as Periactin), in foreign countries. There have been few reports in the country. We have been talking about 8 since November 1979. The case of Cushing’s disease was treated for observation and satisfactory results were obtained. The following analysis was summarized: