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目的 探讨脾原发性恶性肿瘤临床病理特征和手术中无瘤技术原则。方法 结合四例病例报告,回顾性分析脾原发性恶性肿瘤相关临床病理资料,总结出一系列无瘤技术原则和手术方法。结果 本组病例均完成了手术切除,并经病理证实,其中脾恶性纤维组织细胞瘤(MFH)1例,非何杰金氏淋巴瘤(NHL)3例,术后生存最长者4年5个月仍健在。结论 本病治疗的基本术式为脾加胰体尾部切除术;术中操作应严格遵循无瘤术原则。术后辅助性化疗能够对生存率有一定的提高。
Objective To investigate the clinicopathological characteristics of spleen primary malignant tumors and the principle of no-tumor surgery. Methods Combined with four case reports, retrospective analysis of clinical pathological data of splenic primary malignant tumors, summed up a series of no-tumor techniques and surgical methods. RESULTS: All patients underwent surgical resection and confirmed by pathology. One splenic fibrous histiocytoma (MFH) and three non-Hodgkin’s lymphoma (NHL) were included. The longest postoperative survival was 4 years. 5 Month is still alive. Conclusions The basic surgical treatment of this disease is spleen plus pancreatic body caudal resection; the operation should be strictly followed the principle of no tumor surgery. Postoperative adjuvant chemotherapy can improve the survival rate.