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白血病和淋巴瘤在内科治疗中可并发高尿酸血症性急性肾功能衰竭(肾衰),以及肌肉运动后可产生中度高尿酸血症已被人们所认识。本文报告长时间的癫痫发作后引起高尿酸血症性肾衰7例。其中男4例,女3例。2例是癫痫持续状态,另5例是在2~4小时内反复癫痫大发作而急诊入院的。入院后立即用苯巴比妥或安定控制癫痫发作,然后进行血氧、二氧化碳、尿素、尿酸和电解质测定。限制蛋白质饮食直到尿素下降为止,注意体液和电解质平衡。2例因血尿素浓度迅速升高而施行血液透析。
Leukemias and lymphomas may be associated with hyperuricemic acute renal failure (renal failure) during medical therapy and moderate hyperuricemia after muscle exercise has been recognized. This article reports 7 cases of hyperuricemic renal failure after prolonged epileptic seizures. There were 4 males and 3 females. 2 cases of status epilepticus, and the other 5 cases were recurrent epileptic seizures within 2 to 4 hours and emergency admission. Phenobarbital or diazepam was used to control seizures immediately after admission, followed by oximetry, carbon dioxide, urea, uric acid and electrolytes. Limit protein diet until urea drops, pay attention to body fluid and electrolyte balance. 2 cases of hemodialysis due to the rapid increase in blood urea concentration.